STXBP1 antibody (Middle Region)

Catalog No. ABIN2792301

This Rabbit Polyclonal antibody specifically detects STXBP1 in WB. It exhibits reactivity toward Human, Cow, Dog, Zebrafish (Danio rerio), Rabbit, Guinea Pig and Horse.

Quick Overview for STXBP1 antibody (Middle Region) (ABIN2792301)

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Reactivity: Human, Cow, Dog, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STXBP1 Antibody

Binding Specificity: Middle Region

Purpose: STXBP1 Antibody - middle region

Sequence: TRSSASFSTT AVSARYGHWH KNKAPGEYRS GPRLIIFILG GVSLNEMRCA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against STXBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human STXBP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for STXBP1

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Alternative Name: STXBP1

Background:

Background Information: STXBP1 belongs to the STXBP/unc-18/SEC1 family. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4.

Gene Name: Syntaxin binding protein 1

Alternative Symbols: P67, DEE4, NSEC1, UNC18, N-Sec1, RBSEC1, unc-18A, unc18-1, MUNC18-1

Protein Name: Syntaxin-binding protein 1

Molecular Weight: 67kDa

Gene ID: 6812

NCBI Accession: NP_001027392

UniProt: P61764

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport