CTNNB1 antibody (N-Term)

Catalog No. ABIN2792526

The Rabbit Polyclonal anti-CTNNB1 antibody (ABIN2792526) specifically detects CTNNB1 in WB. The antibody is reactive with Human, Mouse, Dog, Zebrafish (Danio rerio), Rabbit, Horse and Guinea Pig samples.

Quick Overview for CTNNB1 antibody (N-Term) (ABIN2792526)

Target: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Reactivity: Human, Mouse, Dog, Zebrafish (Danio rerio), Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNNB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CTNNB1 Antibody

Binding Specificity: N-Term

Sequence: SLSGKGNPEE EDVDTSQVLY EWEQGFSQSF TQEQVADIDG QYAMTRAQRV

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against CTNNB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CTNNB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 781 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CTNNB1

Target: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Alternative Name: CTNNB1 / Beta Catenin

Background: CTNNB1 is involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.
Alias Symbols: CTNNB
Protein Interaction Partner: PPARD, PLA2G4A, FBXO45, BTRC, SUMO1, UBC, HUWE1, CDH5, CDH2, TCF4, TBL1X, SOX1, SKP1, RNF220, CACYBP, FBXW11, SUMO2, SIAH1, Apc2, COPS5, RNF14, CDH1, SP1, KCTD1, MDM2, UBE2B, GSK3B, NEK2, RBX1, PTGS2, STRN3, LATS2, APC, ELAVL1, AMOT, ABL1, AXIN1, CBL, LEF
Protein Size: 781

Molecular Weight: 85 kDa

Gene ID: 1499

NCBI Accession: NM_001904, NP_001895

UniProt: P35222

Pathways: WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2