PAX2A antibody (Middle Region)

Catalog No. ABIN2792620

The Rabbit Polyclonal anti-PAX2A antibody has been validated for WB and IHC. It is suitable to detect PAX2A in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Rabbit, Sheep and Guinea Pig.

Quick Overview for PAX2A antibody (Middle Region) (ABIN2792620)

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Rabbit, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PAX2A Antibody

Binding Specificity: Middle Region

Sequence: VSSASNDPVG SYSINGILGI PRSNGEKRKR DEDVSEGSVP NGDSQSGVDS

Cross-Reactivity: Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PAX2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PAX2

Application Details

Application Notes: WB Suggested Anti-PAX2 Antibody Titration: 1.0 µg/mL
ELISA Titer: 1:312500
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 417 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAX2A

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Alternative Name: PAX2

Background: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.
Protein Interaction Partner: BBS7, BBS4, BBS2, BBS1, RB1, BRCA1, SFRP2, PAXIP1, WT1, MAPK8IP1, MAPK8, ID2,
Protein Size: 417

Molecular Weight: 45 kDa

Gene ID: 5076

NCBI Accession: NM_003988, NP_003979

UniProt: Q02962

Pathways: Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation