CSDA antibody (N-Term)

Catalog No. ABIN184337

The Rabbit Polyclonal anti-CSDA antibody is suitable to detect CSDA in samples from Human, Mouse, Pig, Rat, Cow, Dog and Guinea Pig. It has been validated for WB.

Quick Overview for CSDA antibody (N-Term) (ABIN184337)

Target: CSDA (Cold Shock Domain Protein A (CSDA))

Reactivity: Human, Mouse, Pig, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSDA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CSDA Antibody

Binding Specificity: N-Term

Sequence: AHVAGNPGGD AAPAATGTAA AASLAAAAGS EDAEKKVLAT KVLGTVKWFN

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 84%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CSDA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CSDA

Application Details

Application Notes: WB Suggested Anti-CSDA Antibody Titration: 1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 372 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CSDA

Target: CSDA (Cold Shock Domain Protein A (CSDA))

Alternative Name: DNA-binding protein A

Background: Human DNA-binding protein (dbpA) is a member of a Y-box binding protein family containing a cold shock domain. The increased expression of Y box binding proteins in somatic cells is associated with cell proliferation and transformation.
Alias Symbols: DBPA, CSDA1, ZONAB
Protein Interaction Partner: CEP76, CEP250, UBC, SUZ12, RNF2, EZH2, BMI1, C14orf166, RTCB, NELFB, MACF1, IGF2BP3, EIF5B, MAP7, EIF2B2, EIF2B3, RFC4, PTBP1, NMT1, MRE11A, ILF2, HNRNPU, DHX9, DDX1, CSRP1, ABCF1, PARK2, SRPK3, TARDBP, ICAM1, IGSF8, HDAC11, PAN2, IL7R, IFIT3, IFIT2, ESR1
Protein Size: 372

Molecular Weight: 40 kDa

Gene ID: 8531

NCBI Accession: NM_003651, NP_003642

UniProt: P16989

Pathways: Negative Regulation of intrinsic apoptotic Signaling