IRF2 antibody (N-Term)

Catalog No. ABIN2792666

This Rabbit Polyclonal antibody specifically detects IRF2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig and Sheep.

Quick Overview for IRF2 antibody (N-Term) (ABIN2792666)

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IRF2 Antibody

Binding Specificity: N-Term

Sequence: IEEVKDKSIK KGNNAFRVYR MLPLSERPSK KGKKPKTEKE DKVKHIKQEP

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against IRF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF2

Application Details

Application Notes: WB Suggested Anti-IRF2 Antibody Titration: 5.0 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IRF2

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Alternative Name: IRF2

Background: IRF2 is a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.
Alias Symbols: IRF-2
Protein Interaction Partner: IRF1, SUMO2, SUMO3, PRDM1, MDM2, FKBP7, HSP90AA1, APP, IRF2BP2, IRF2BP1, UBC, FOXK1, IRF2BPL, HCFC2, ATG7, AP5Z1, PPP3CB, PPP3CA, FOXK2, HCFC1, KAT2B, EP300, IRF8, STAT1, RELA, NFKB1, HMGN1, HMGB1, CSNK2A1, BRD7, PRKACA, KAT2A,
Protein Size: 349

Molecular Weight: 39 kDa

Gene ID: 3660

NCBI Accession: NM_002199, NP_002190

UniProt: P14316