LMO2 antibody (N-Term)

Catalog No. ABIN2792668

The Rabbit Polyclonal anti-LMO2 antibody (ABIN2792668) specifically detects LMO2 in WB. The antibody is reactive with Mouse, Rat, Dog, Guinea Pig and Rabbit samples.

Quick Overview for LMO2 antibody (N-Term) (ABIN2792668)

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Reactivity: Mouse, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMO2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LMO2 Antibody

Binding Specificity: N-Term

Purpose: LMO2 Antibody - N-terminal region

Sequence: GGGARAPEGV RAPAAGQPRA TKGAPPPPGT PPPSPMSSAI ERKSLDPSEE

Cross-Reactivity: Cow (Bovine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LMO2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LMO2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Alternative Name: LMO2

Background:

Background Information: LMO2 acts with TAL1/SCL to regulate red blood cell development. LMO2 also acts with LDB1 to maintain erythroid precursors in an immature state.LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: LIM domain only 2 (rhombotin-like 1)

Alternative Symbols: TTG2, LMO-2, RBTN2, RHOM2, RBTNL1

Protein Name: Rhombotin-2

Molecular Weight: 18kDa

Gene ID: 4005

NCBI Accession: NP_005565

UniProt: P25791

Pathways: Chromatin Binding