NFIC antibody (Middle Region)

Catalog No. ABIN2792686

The Rabbit Polyclonal anti-NFIC antibody is suitable to detect NFIC in samples from Human, Mouse, Rat, Dog, Cow and Guinea Pig. It has been validated for WB and IHC.

Quick Overview for NFIC antibody (Middle Region) (ABIN2792686)

Target: NFIC (Nuclear Factor I/C (CCAAT-Binding Transcription Factor) (NFIC))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFIC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NFIC Antibody

Binding Specificity: Middle Region

Sequence: KSPFNSPSPQ DSPRLSSFTQ HHRPVIAVHS GIARSPHPSS ALHFPTTSIL

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NFIC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NFIC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 499 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NFIC

Target: NFIC (Nuclear Factor I/C (CCAAT-Binding Transcription Factor) (NFIC))

Alternative Name: NFIC

Background: Brg- or hBrm-associated factor (BAF) complexes, a chromatin-remodeling complex family of mammalian cells, facilitate transcriptional activity by remodeling nucleosome structure. Brg1 is the core subunit of Brg-associated factor complexes. BAF complexes can interact with NF1/CTF and RNAP II, and this interaction is closely dependent on the activation of gene transcription.
Alias Symbols: CTF, CTF5, MGC20153, NF-I, NFI
Protein Interaction Partner: HSP90AA1, TFAP4, Cebpb, ELAVL1, SUMO2, UBC, SMURF1, SMAD3, ZCCHC14, ZKSCAN7, TPD52L3, TKTL2, LLPH, NFIB, GLRX, CREBBP, RFX1, TLX1,
Protein Size: 499

Molecular Weight: 55 kDa

Gene ID: 4782

NCBI Accession: NM_205843, NP_995315

UniProt: Q6FI30