PDX1 antibody (C-Term)

Catalog No. ABIN2793201

This anti-PDX1 antibody is a Rabbit Polyclonal antibody detecting PDX1 in WB, IF and IP. Suitable for Human.

Quick Overview for PDX1 antibody (C-Term) (ABIN2793201)

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-PDX1 Antibody

Binding Specificity: AA 186-215, C-Term

Purpose: Rabbit Anti-Human IPF (C-term) Antibody

Immunogen: This IPF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the C-terminal region of human IPF.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IF: 1:10-50Ipf Antibody (C-term) . IPF immunoreactivity is localized to Cytoplasm and Nucleus significantly.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PDX1

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Alternative Name: IPF

Background:

Target Description: IPF is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Gene Symbol: PDX1

Molecular Weight: 30771 Da

Gene ID: 3651

UniProt: P52945

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location