CFLA antibody (Center)

Catalog No. ABIN2793618

This anti-CFLA antibody is a Rabbit Polyclonal antibody detecting CFLA in FACS, IHC and WB. Suitable for Human.

Quick Overview for CFLA antibody (Center) (ABIN2793618)

Target: CFLA (VVL) (POU Domain Protein CF1A (VVL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-CFLA Antibody

Binding Specificity: AA 145-174, Center

Purpose: Rabbit Anti-Human CFLAR (Center) Antibody

Immunogen: This CFLAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human CFLAR.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, FC: 1:10-50Western blot analysis of CFLAR Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.000 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CFLA

Target: CFLA (VVL) (POU Domain Protein CF1A (VVL))

Alternative Name: CFLA

Background:

Target Description: Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.

Gene Symbol: CFLAR

Molecular Weight: 55344 Da

Gene ID: 8837

UniProt: O15519