Src antibody (N-Term)
Quick Overview for Src antibody (N-Term) (ABIN2793858)
Target
See all Src AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 24-52, N-Term
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Purpose
- Rabbit Anti-Human SRC (N-term) Antibody
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Immunogen
- This SRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human SRC.
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Isotype
- Ig Fraction
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Application Notes
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Western Blot, Immunohistochemistry, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:2000, IHC: 1:50, FC: 1:50, IF: 1:50SRC Antibody (N-term) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.500 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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Alternative Name
- SRC
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Background
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Target Description: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Gene Symbol: SRC
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Molecular Weight
- 59835 Da
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Gene ID
- 6714
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UniProt
- P12931
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Pathways
- JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Target
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