SPANXB1 antibody (Center)

Catalog No. ABIN2796039

The Rabbit Polyclonal anti-SPANXB1 antibody (ABIN2796039) specifically detects SPANXB1 in WB. The antibody is reactive with Human samples.

Quick Overview for SPANXB1 antibody (Center) (ABIN2796039)

Target: SPANXB1 (SPANX Family, Member B1 (SPANXB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPANXB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPANXB1 Antibody

Binding Specificity: AA 17-47, Center

Purpose: Rabbit Anti-Human SPNXB (Center) Antibody

Immunogen: This SPNXB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the Central region of human SPNXB.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000SPNXB Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for SPANXB1

Target: SPANXB1 (SPANX Family, Member B1 (SPANXB1))

Alternative Name: SPNXB

Background:

Target Description: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B1 and appears to be a duplication of that locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis.

Gene Symbol: SPANXB1

Molecular Weight: 11826 Da

Gene ID: 728695

UniProt: Q9NS25