RSPH1 antibody (C-Term)

Catalog No. ABIN2796441

Product Details anti-RSPH1 Antibody

Target: RSPH1 (Radial Spoke Head 1 Homolog (RSPH1))

Binding Specificity: AA 532-558, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSPH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit Anti-Human MCAM (C-term) Antibody

Immunogen: This MCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-558 amino acids from the C-terminal region of human MCAM.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of MCAM Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.300 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for RSPH1

Target: RSPH1 (Radial Spoke Head 1 Homolog (RSPH1))

Alternative Name: MCA (RSPH1 Products)

Synonyms: TSGA2 antibody, RSP44 antibody, RSPH10A antibody, TSA2 antibody, MCA antibody, Tsga2 antibody, radial spoke head 1 homolog antibody, radial spoke head 1 homolog (Chlamydomonas) antibody, RSPH1 antibody, Rsph1 antibody

Background:

Target Description: MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Gene Symbol: MCAM

Molecular Weight: 71607 Da

Gene ID: 4162

UniProt: P43121