KREMEN2 antibody (Center)
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- Target See all KREMEN2 Antibodies
- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
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Binding Specificity
- AA 248-276, Center
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KREMEN2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit Anti-Human KREMEN2 (Center) Antibody
- Immunogen
- This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product KREMEN2 Primary Antibody
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- Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000KREMEN2 Antibody (Center) . - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
- Alternative Name
- KREMEN2 (KREMEN2 Products)
- Background
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Target Description: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Gene Symbol: KREMEN2
- Molecular Weight
- 48849 Da
- Gene ID
- 79412
- UniProt
- Q8NCW0
- Pathways
- WNT Signaling
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