RNF19A antibody (Center)

Catalog No. ABIN2798497

This Rabbit Polyclonal antibody specifically detects RNF19A in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for RNF19A antibody (Center) (ABIN2798497)

Target: RNF19A (Ring Finger Protein 19A (RNF19A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF19A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RNF19A Antibody

Binding Specificity: AA 384-413, Center

Purpose: Rabbit Anti-Human RNF19A (Center) Antibody

Immunogen: This RNF19A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-413 amino acids from the Central region of human RNF19A.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50RNF19A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for RNF19A

Target: RNF19A (Ring Finger Protein 19A (RNF19A))

Alternative Name: RNF19A

Background:

Target Description: The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.

Gene Symbol: RNF19A

Molecular Weight: 90696 Da

Gene ID: 25897

UniProt: Q9NV58