RNF19A antibody (AA 30-110)

Catalog No. ABIN7220922

This Rabbit Polyclonal antibody specifically detects RNF19A in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for RNF19A antibody (AA 30-110) (ABIN7220922)

Target: RNF19A (Ring Finger Protein 19A (RNF19A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF19A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RNF19A Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-Dorfin Polyclonal Antibody

Specificity: Dorfin Polyclonal Antibody detects endogenous levels of Dorfin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Dorfin at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RNF19A

Target: RNF19A (Ring Finger Protein 19A (RNF19A))

Alternative Name: Dorfin

Background: RNF19A, RNF19, E3 ubiquitin-protein ligase RNF19A, Double ring-finger protein, Dorfin, RING finger protein 19A, p38RNF19A encodes a member of the ring between ring fingers (RBR) protein family, and the ring finger protein 19A, RBR E3 ubiquitin protein ligase contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants.

Molecular Weight: 90kD

Gene ID: 25897

UniProt: Q9NV58