RNF19A antibody (AA 741-825)

Catalog No. ABIN7151172

Product Details anti-RNF19A Antibody

Target: RNF19A (Ring Finger Protein 19A (RNF19A))

Binding Specificity: AA 741-825

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF19A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase RNF19A protein (741-825AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNF19A

Target: RNF19A (Ring Finger Protein 19A (RNF19A))

Alternative Name: RNF19A (RNF19A Products)

Synonyms: RNF19 antibody, RNF19A antibody, AA032313 antibody, Dorfin antibody, Rnf19 antibody, UIP117 antibody, Ubce7ip2 antibody, XYbp antibody, ring finger protein 19A, RBR E3 ubiquitin protein ligase antibody, ring finger protein 19A antibody, RNF19A antibody, Rnf19a antibody

Background:

Background: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.

Aliases: AA032313 antibody, DKFZP566B1346 antibody, Dorfin antibody, Double ring finger protein antibody, Double ring-finger protein antibody, E3 ubiquitin-protein ligase RNF19A antibody, p38 antibody, p38 protein antibody, Ring finger protein 19 antibody, RING finger protein 19A antibody, Ring IBR ring domain containing protein Dorfin antibody, RN19A_HUMAN antibody, RNF19 antibody, RNF19A antibody, Ubce7ip2 antibody, UIP117 antibody, XYbp antibody

UniProt: Q9NV58