T-Bet antibody (N-Term)

Catalog No. ABIN2798591

The Rabbit Polyclonal anti-T-Bet antibody has been validated for WB and IF. It is suitable to detect T-Bet in samples from Human.

Quick Overview for T-Bet antibody (N-Term) (ABIN2798591)

Target: T-Bet

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Bet antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-T-Bet Antibody

Binding Specificity: AA 22-50, N-Term

Purpose: Rabbit Anti-Human TBX21 (N-term) Antibody

Immunogen: This TBX21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human TBX21.

Isotype: Ig Fraction

Application Details

Application Notes: Immunofluorescence, Western Blot
Recommended Dilutions
IF: 1:10-50, WB: 1:1000Fluorescent image of A549 cell stained with TBX21 Antibody (N-term).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.500 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for T-Bet

Target: T-Bet

Alternative Name: TBX21

Background:

Target Description: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.

Gene Symbol: TBX21

Molecular Weight: 58328 Da

Gene ID: 30009

UniProt: Q9UL17