ASK1 antibody (C-Term)

Catalog No. ABIN2798599

This Rabbit Polyclonal antibody specifically detects ASK1 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for ASK1 antibody (C-Term) (ABIN2798599)

Target: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ASK1 Antibody

Binding Specificity: AA 1175-1203, C-Term

Purpose: Rabbit Anti-Mouse Map3k5 (C-term) Antibody

Immunogen: This Mouse Map3k5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1175-1203 amino acids from the C-terminal region of mouse Map3k5.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of Map3k5 (arrow) using rabbit polyclonal Mouse Map3k5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.290 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for ASK1

Target: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Alternative Name: Map3k5

Background:

Target Description: Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death (By similarity).

Gene Symbol: Map3k5

Molecular Weight: 154512 Da

Gene ID: 26408

UniProt: O35099

Pathways: MAPK Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response