KDM5B antibody (N-Term)

Catalog No. ABIN2798607

This anti-KDM5B antibody is a Rabbit Polyclonal antibody detecting KDM5B in WB. Suitable for Mouse.

Quick Overview for KDM5B antibody (N-Term) (ABIN2798607)

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM5B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KDM5B Antibody

Binding Specificity: AA 192-224, N-Term

Purpose: Rabbit Anti-Mouse JARID1B (N-term) Antibody

Immunogen: This JARID1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-224 amino acids from the N-terminal region of human JARID1B.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000JARID1B Antibody (N-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.410 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for KDM5B

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Alternative Name: JARID1B

Background:

Target Description: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.

Gene Symbol: KDM5B

Molecular Weight: 175658 Da

Gene ID: 10765

UniProt: Q9UGL1

Pathways: Warburg Effect