E2F3 antibody (Center)

Catalog No. ABIN2798668

This Rabbit Polyclonal antibody specifically detects E2F3 in WB. It exhibits reactivity toward Human.

Quick Overview for E2F3 antibody (Center) (ABIN2798668)

Target: E2F3

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E2F3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-E2F3 Antibody

Binding Specificity: AA 151-180, Center

Purpose: Rabbit Anti-Human E2F3 (Center) Antibody

Immunogen: This E2F3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human E2F3.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000E2F3 Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.350 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for E2F3

Target: E2F3

Background:

Target Description: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.

Gene Symbol: E2F3

Molecular Weight: 49162 Da

Gene ID: 1871

UniProt: O00716