PDE8A antibody (Center)

Catalog No. ABIN2798679

The Rabbit Polyclonal anti-PDE8A antibody (Clone L572) (ABIN2798679) specifically detects PDE8A in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for PDE8A antibody (Center) (ABIN2798679)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE8A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: L572

Product Details anti-PDE8A Antibody

Binding Specificity: AA 557-587, Center

Purpose: Rabbit Anti-Human PDE8A (Center) (L572) Antibody

Immunogen: This PDE8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-587 amino acids from the Central region of human PDE8A.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50Western blot analysis of PDE8A Antibody (Center) (L572) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Alternative Name: PDE8A

Background:

Target Description: PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.

Gene Symbol: PDE8A

Molecular Weight: 93304 Da

Gene ID: 5151

UniProt: O60658

Pathways: cAMP Metabolic Process