GSK3 beta antibody (N-Term)
Quick Overview for GSK3 beta antibody (N-Term) (ABIN2798780)
Target
See all GSK3 beta (GSK3b) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 30-59, N-Term
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Purpose
- Rabbit Anti-Mouse Mouse Gsk3b (N-term) Antibody
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Immunogen
- This Mouse Gsk3b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of mouse Gsk3b.
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Isotype
- Ig Fraction
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Application Notes
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Mouse Gsk3b Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
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Alternative Name
- Gsk3b
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Background
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Target Description: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).
Gene Symbol: Gsk3b
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Molecular Weight
- 46710 Da
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Gene ID
- 56637
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UniProt
- Q9WV60
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Pathways
- WNT Signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect
Target
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