HYAL1 antibody (C-Term)

Catalog No. ABIN2798799

The Rabbit Polyclonal anti-HYAL1 antibody (ABIN2798799) specifically detects HYAL1 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for HYAL1 antibody (C-Term) (ABIN2798799)

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HYAL1 Antibody

Binding Specificity: AA 280-309, C-Term

Purpose: Rabbit Anti-Human HYAL1 (C-term) Antibody

Immunogen: This HYAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human HYAL1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50HYAL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for HYAL1

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Alternative Name: HYAL1

Background:

Target Description: This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Symbol: HYAL1

Molecular Weight: 48368 Da

Gene ID: 3373

UniProt: Q12794

Pathways: Glycosaminoglycan Metabolic Process