RAD51C antibody (Center)

Catalog No. ABIN2798838

This anti-RAD51C antibody is a Rabbit Polyclonal antibody detecting RAD51C in WB. Suitable for Human.

Quick Overview for RAD51C antibody (Center) (ABIN2798838)

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD51C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAD51C Antibody

Binding Specificity: AA 169-198, Center

Purpose: Rabbit Anti-Human RAD51C (Center) Antibody

Immunogen: This RAD51C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RAD51C.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000RAD51C Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Alternative Name: RAD51C

Background:

Target Description: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Gene Symbol: RAD51C

Molecular Weight: 42190 Da

Gene ID: 5889

UniProt: O43502

Pathways: DNA Damage Repair