MXI1 antibody (Center)

Catalog No. ABIN2798843

The Rabbit Polyclonal anti-MXI1 antibody has been validated for WB. It is suitable to detect MXI1 in samples from Mouse.

Quick Overview for MXI1 antibody (Center) (ABIN2798843)

Target: MXI1 (MAX Interactor 1 (MXI1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MXI1 Antibody

Binding Specificity: AA 53-82, Center

Purpose: Rabbit Anti-Mouse MXI1 (Center) Antibody

Immunogen: This MXI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000MXI1 Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MXI1

Target: MXI1 (MAX Interactor 1 (MXI1))

Alternative Name: MXI1

Background:

Target Description: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Gene Symbol: MXI1

Molecular Weight: 26062 Da

Gene ID: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location