ATF3 antibody (C-Term)

Catalog No. ABIN2799112

This Rabbit Polyclonal antibody specifically detects ATF3 in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for ATF3 antibody (C-Term) (ABIN2799112)

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-ATF3 Antibody

Binding Specificity: AA 140-168, C-Term

Purpose: Rabbit Anti-Human ATF3 (C-term) Antibody

Immunogen: This ATF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human ATF3.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50ATF3 Antibody (C-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.300 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for ATF3

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Alternative Name: ATF3

Background:

Target Description: Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.

Gene Symbol: ATF3

Molecular Weight: 20576 Da

Gene ID: 467

UniProt: P18847

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response