ATF3 antibody (AA 1-181)

Catalog No. ABIN559974

Cited in 3+ publications. The Mouse Monoclonal anti-ATF3 antibody (Clone 6B8) (ABIN559974) specifically detects ATF3 in WB, ELISA and RNAi. The antibody is reactive with Human samples.

Quick Overview for ATF3 antibody (AA 1-181) (ABIN559974)

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, RNA Interference (RNAi)

Clone: 6B8

Product Details anti-ATF3 Antibody

Binding Specificity: AA 1-181

Purpose: Mouse monoclonal antibody raised against a full length recombinant ATF3.

Sequence: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ATF3 (AAH06322, 1 a.a. ~ 181 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ATF3 antibody (ABIN559974)

Hsueh, Kuo, Chen: "Transcriptional regulators of the ?Np63: their role in limbal epithelial cell proliferation." in: Journal of cellular physiology, Vol. 228, Issue 3, pp. 536-46, (2012) (PubMed).

Chen, Huang, Chu, Chen, Chou, Wang, Kulp, Teng, Wang, Chen: "Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression." in: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 9968-76, (2011) (PubMed).

Roussel, Robins, Schachter, Bérubé, Hamid, Rousseau: "Steroids and extracellular signal-regulated kinase 1/2 activity suppress activating transcription factor 3 expression in patients with severe asthma." in: The Journal of allergy and clinical immunology, Vol. 127, Issue 6, pp. 1632-4, (2011) (PubMed).

Target Details for ATF3

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Alternative Name: ATF3

Background: Full Gene Name: activating transcription factor 3
Synonyms:

Gene ID: 467

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response