EPO antibody (Center)

Catalog No. ABIN2799146

The Rabbit Polyclonal anti-EPO antibody has been validated for WB, FACS and IF. It is suitable to detect EPO in samples from Human.

Quick Overview for EPO antibody (Center) (ABIN2799146)

Target: EPO (Erythropoietin (EPO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPO antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-EPO Antibody

Binding Specificity: AA 329-357, Center

Purpose: Rabbit Anti-Human EPOR (Center) Antibody

Immunogen: This EPOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human EPOR.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, FC: 1:10-50, IF: 1:10-50EPOR Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.300 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for EPO

Target: EPO (Erythropoietin (EPO))

Alternative Name: EPO

Target Type: Hormone

Background:

Target Description: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Gene Symbol: EPOR

Molecular Weight: 55065 Da

Gene ID: 2057

UniProt: P19235

Pathways: JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity