ADCY9 antibody

Catalog No. ABIN1944823

This Rabbit Polyclonal antibody specifically detects ADCY9 in WB and IHC. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for ADCY9 antibody (ABIN1944823)

Target: ADCY9 (Adenylate Cyclase 9 (ADCY9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ADCY9 Antibody

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000. IHC: 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C,-20 °C

References for anti-ADCY9 antibody (ABIN1944823)

Tantisira, Small, Litonjua, Weiss, Liggett: "Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways." in: Human molecular genetics, Vol. 14, Issue 12, pp. 1671-7, (2005) (PubMed).

Small, Brown, Theiss, Seman, Weiss, Liggett: "An Ile to Met polymorphism in the catalytic domain of adenylyl cyclase type 9 confers reduced beta2-adrenergic receptor stimulation." in: Pharmacogenetics, Vol. 13, Issue 9, pp. 535-41, (2003) (PubMed).

Hacker, Tomlinson, Wayman, Sultana, Chan, Villacres, Disteche, Storm: "Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9)." in: Genomics, Vol. 50, Issue 1, pp. 97-104, (1999) (PubMed).

Target Details for ADCY9

Target: ADCY9 (Adenylate Cyclase 9 (ADCY9))

Alternative Name: ADCY9

Background: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity).

Molecular Weight: 150701 Da

Gene ID: 115

UniProt: O60503

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma