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PDX1 antibody (AA 188-284) (AbBy Fluor® 594)

The Rabbit Polyclonal anti-PDX1 antibody has been validated for WB, IF (p) and IF (cc). It is suitable to detect PDX1 in samples from Rat and Goat.
Catalog No. ABIN2803407

Quick Overview for PDX1 antibody (AA 188-284) (AbBy Fluor® 594) (ABIN2803407)

Target

See all PDX1 Antibodies
PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reactivity

  • 107
  • 43
  • 35
  • 14
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Rat, Goat

Host

  • 121
  • 8
  • 2
Rabbit

Clonality

  • 115
  • 16
Polyclonal

Conjugate

  • 66
  • 10
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PDX1 antibody is conjugated to AbBy Fluor® 594

Application

  • 83
  • 55
  • 30
  • 17
  • 15
  • 14
  • 13
  • 13
  • 6
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • Binding Specificity

    • 16
    • 14
    • 10
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 188-284

    Cross-Reactivity

    Goat, Rat

    Predicted Reactivity

    Human,Mouse,Pig,Chicken

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from mouse PDX1

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

    Alternative Name

    PDX1

    Background

    Synonyms: Ipf1, IDX-1, IPF-1, Mody4, STF-1, pdx-1, Pancreas/duodenum homeobox protein 1, Insulin promoter factor 1, Islet/duodenum homeobox 1, Somatostatin-transactivating factor 1, Pdx1

    Background: Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3'.

    Gene ID

    18609

    UniProt

    P52946

    Pathways

    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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