Kallikrein 7 antibody (AA 101-200) (AbBy Fluor® 594)
Quick Overview for Kallikrein 7 antibody (AA 101-200) (AbBy Fluor® 594) (ABIN2803623)
Target
See all Kallikrein 7 (KLK7) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 101-200
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Cross-Reactivity
- Rat
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Predicted Reactivity
- Human,Mouse,Dog,Cow,Pig
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human KLK7
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Isotype
- IgG
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Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- Kallikrein 7 (KLK7)
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Alternative Name
- KLK7
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Background
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Synonyms: hK7, SCCE, PRSS6, Kallikrein-7, Serine protease 6, Stratum corneum chymotryptic enzyme, hSCCE, KLK7
Background: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
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Gene ID
- 5650
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UniProt
- P49862
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Pathways
- Complement System
Target
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