LSAMP antibody (AA 51-150) (AbBy Fluor® 594)

Catalog No. ABIN2803871

This Rabbit Polyclonal antibody specifically detects LSAMP in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for LSAMP antibody (AA 51-150) (AbBy Fluor® 594) (ABIN2803871)

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSAMP antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-LSAMP Antibody (AbBy Fluor® 594)

Binding Specificity: AA 51-150

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LSAMP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LSAMP

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Alternative Name: LSAMP

Background:

Synonyms: IgLON family member 3, IGLON3, Lam, LAMP, Limbic system associated membrane protein, Limbic system associated membrane protein precursor, Limbic system-associated membrane protein, LSAMP, LSAMP_HUMAN.

Background: LSAMP is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system expressed on the surface of somata and proximal dendrites of neurons. It is a member of the immunoglobulin (Ig) superfamily and belongs to the IgLON subfamily of cell adhesion molecules. LSAMP contains three Ig domains and a glycosylphosphatidylinositol anchor. It is a highly conserved protein between rodents and humans (99 % sequence identity) and it is involved in the regulation of neurite outgrowth and mediation of proper circuit formation of limbic pathways. This suggests that LSAMP plays an important role in the development and function of the limbic system. In addition, LSAMP may function as a tumor suppressor in renal carcinomas.