REC8 antibody (pSer251) (AbBy Fluor® 594)

Catalog No. ABIN2805875

This anti-REC8 antibody is a Rabbit Polyclonal antibody detecting REC8 in WB, IF (cc) and IF (p). Suitable for Mouse and Rat.

Quick Overview for REC8 antibody (pSer251) (AbBy Fluor® 594) (ABIN2805875)

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REC8 antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-REC8 Antibody (AbBy Fluor® 594)

Binding Specificity: pSer251

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse REC8 around the phosphorylation site of Ser251

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for REC8

Target: REC8 (REC8 Homolog (Yeast) (REC8))

Alternative Name: REC8

Background:

Synonyms: mrec, Rec8L1, Meiotic recombination protein REC8 homolog, Cohesin Rec8p, Rec8, Mei8

Background: Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.

Gene ID: 56739

UniProt: Q8C5S7