CNIH2, CNIH3 (AA 25-120) antibody (AbBy Fluor® 594)
Quick Overview for CNIH2, CNIH3 (AA 25-120) antibody (AbBy Fluor® 594) (ABIN2811771)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 25-120
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Specificity
- This antibody detects both CNIH2 and CNIH3 proteins
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Cross-Reactivity
- Rat
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Predicted Reactivity
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CNIH2/CNIH3
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Isotype
- IgG
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anti-CNIH2, CNIH3 (AA 25-120) antibody
Reactivity: Rat WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
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Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- CNIH2, CNIH3
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Alternative Name
- CNIH2/3
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Background
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Synonyms: Protein cornichon homolog 2, CNIH2, Cornichon family AMPA receptor auxiliary protein 2, Protein cornichon homolog 3, CNIH3, Cornichon family AMPA receptor auxiliary protein 3
Background: CNIH2 and CNIH3 regulate the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). They promote their targeting to the cell membrane and synapses and modulate their gating properties by regulating their rates of activation, deactivation and desensitization. CNIH2 also blocks CACNG8-mediated resensitization of AMPA receptors.
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Gene ID
- 254263, 149111
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UniProt
- Q6PI25, Q8TBE1
Target
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