DSCR3 antibody (AA 1-100) (HRP)

Catalog No. ABIN2815017

This Rabbit Polyclonal antibody specifically detects DSCR3 in IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for DSCR3 antibody (AA 1-100) (HRP) (ABIN2815017)

Target: DSCR3 (Down Syndrome Critical Region Gene 3 (DSCR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DSCR3 antibody is conjugated to HRP

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DSCR3 Antibody (HRP)

Binding Specificity: AA 1-100

Purpose: DSCR3 Polyclonal Antibody, HRP Conjugated

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DSCR3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DSCR3

Target: DSCR3 (Down Syndrome Critical Region Gene 3 (DSCR3))

Alternative Name: DSCR3

Background:

Synonyms: DCRA, DSCRA, Down syndrome critical region protein 3, Down syndrome critical region protein A, DSCR3

Background: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]

Gene ID: 10311

UniProt: O14972