ACSL6 antibody (AA 240-270)

Catalog No. ABIN2839301

The Rabbit Polyclonal anti-ACSL6 antibody (Clone RB4703) (ABIN2839301) specifically detects ACSL6 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for ACSL6 antibody (AA 240-270) (ABIN2839301)

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACSL6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB4703

Product Details anti-ACSL6 Antibody

Binding Specificity: AA 240-270

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FACL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-270 amino acids from the Central region of human FACL6.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ACSL6

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Alternative Name: FACL6

Background: FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5,12)(q31,p13) that involves ETV6 and ACSL6.

Molecular Weight: 77752

Gene ID: 23305

NCBI Accession: NP_001009185, NP_001192176, NP_001192177, NP_001192179, NP_001192180, NP_056071

UniProt: Q9UKU0