TNIK antibody (pSer764)

Catalog No. ABIN389674

This Rabbit Polyclonal antibody specifically detects TNIK in IHC (p) and DB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for TNIK antibody (pSer764) (ABIN389674)

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIK antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Clone: RB7150

Product Details anti-TNIK Antibody

Binding Specificity: pSer764

Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S764 of human TNIK.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNIK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S764 of human TNIK.

Isotype: Ig Fraction

Application Details

Application Notes: DB = 1:500, IHC (p) = 1:50-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.375 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-TNIK antibody (ABIN389674)

Wang, Charych, Pulito, Lee, Graziane, Crozier, Revilla-Sanchez, Kelly, Dunlop, Murdoch, Taylor, Xie, Pausch, Hayashi-Takagi, Ishizuka, Seshadri, Bates, Kariya, Sawa, Weinberg, Moss, Houslay, Yan et al.: "The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. ..." in: Molecular psychiatry, Vol. 16, Issue 10, pp. 1006-23, (2011) (PubMed).

Target Details for TNIK

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Alternative Name: TNIK

Background: Synonyms: TRAF2 and NCK-interacting kinase, TNIK, KIAA0551,

Molecular Weight: 154943 DA

Gene ID: 23043

UniProt: Q9UKE5