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TNIK antibody (pSer764)

TNIK Reactivity: Mouse, Rat ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN711941
  • Target See all TNIK Antibodies
    TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
    Binding Specificity
    • 23
    • 15
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pSer764
    Reactivity
    • 77
    • 54
    • 36
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 104
    • 3
    Rabbit
    Clonality
    • 104
    • 3
    Polyclonal
    Conjugate
    • 39
    • 10
    • 9
    • 9
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This TNIK antibody is un-conjugated
    Application
    • 50
    • 43
    • 28
    • 26
    • 26
    • 19
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Phosphorylation site corresponds to Ser735 in mouse
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764
    Isotype
    IgG
    Top Product
    Discover our top product TNIK Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
    Alternative Name
    TNIK (TNIK Products)
    Synonyms
    RGD1561817 antibody, TNIK antibody, 1500031A17Rik antibody, 4831440I19Rik antibody, AI451411 antibody, C530008O15Rik antibody, C630040K21Rik antibody, fc52d11 antibody, msn antibody, tnikl antibody, wu:fc52d11 antibody, zgc:63535 antibody, im:6898857 antibody, zgc:123033 antibody, zgc:152783 antibody, tnik antibody, TRAF2 and NCK interacting kinase antibody, TRAF2 and NCK interacting kinase a antibody, TRAF2 and NCK interacting kinase b antibody, TRAF2 and NCK interacting kinase S homeolog antibody, TNIK antibody, Tnik antibody, tnika antibody, tnikb antibody, tnik.S antibody
    Background

    Synonyms: TRAF2 and NCK-interacting protein kinase, TNIK, KIAA0551

    Background: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.

    Gene ID
    23043
    UniProt
    Q9UKE5
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