FMR1 antibody (N-Term)

Catalog No. ABIN2841083

The Rabbit Polyclonal anti-FMR1 antibody has been validated for WB, IHC (p) and FACS. It is suitable to detect FMR1 in samples from Human and Mouse. There is 1 publication available.

Quick Overview for FMR1 antibody (N-Term) (ABIN2841083)

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FMR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB20964

Product Details anti-FMR1 Antibody

Binding Specificity: AA 20-48, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FMR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from the N-terminal region of human FMR1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-FMR1 antibody (ABIN2841083)

Majumder, House, Palanisamy, Qie, Day, Neskey, Diehl, Palanisamy: "RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC." in: PLoS genetics, Vol. 12, Issue 9, pp. e1006306, (2017) (PubMed).

Target Details for FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Alternative Name: FMR1

Background: FMR1 binds RNA and is associated with polysomes. This protein may be involved in mRNA trafficking from the nucleus to the cytoplasm.

Molecular Weight: 71174

Gene ID: 2332

NCBI Accession: NP_001172004, NP_001172005, NP_001172010, NP_001172011, NP_002015

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development