BRD3 antibody (C-Term)

Catalog No. ABIN2842132

Cited in 1 publication. The Rabbit Polyclonal anti-BRD3 antibody (Clone RB3471) (ABIN2842132) specifically detects BRD3 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for BRD3 antibody (C-Term) (ABIN2842132)

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB3471

Product Details anti-BRD3 Antibody

Binding Specificity: AA 672-702, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This BRD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 672-702 amino acids from the C-terminal region of human BRD3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-BRD3 antibody (ABIN2842132)

Klein, Kabala, Grabiec, Gay, Kolling, Lin, Gay, Tak, Prinjha, Ospelt, Reedquist: "The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts." in: Annals of the rheumatic diseases, (2014) (PubMed).

Target Details for BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Alternative Name: BRD3

Background: This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.

Molecular Weight: 79542

Gene ID: 8019

NCBI Accession: NP_031397

UniProt: Q15059

Pathways: Chromatin Binding