ITGA6 antibody (C-Term)

Catalog No. ABIN2842747

Cited in 1 publication. The Rabbit Polyclonal anti-ITGA6 antibody (Clone RB18006) (ABIN2842747) specifically detects ITGA6 in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for ITGA6 antibody (C-Term) (ABIN2842747)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18006

Product Details anti-ITGA6 Antibody

Binding Specificity: AA 1082-1110, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CD49f antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1082-1110 amino acids from the C-terminal region of human CD49f.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ITGA6 antibody (ABIN2842747)

He, Yang, Li: "The clinical pathological significance of Thy1 and CD49f expression in chondrosarcomas." in: Pathology, research and practice, Vol. 212, Issue 7, pp. 636-42, (2017) (PubMed).

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: CD49f

Background: The CD49f protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Molecular Weight: 126606

Gene ID: 3655

NCBI Accession: NP_000201, NP_001073286

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex