TNIP1 antibody (C-Term)

Catalog No. ABIN2844618

The Rabbit Polyclonal anti-TNIP1 antibody (Clone RB28148) (ABIN2844618) specifically detects TNIP1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TNIP1 antibody (C-Term) (ABIN2844618)

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB28148

Product Details anti-TNIP1 Antibody

Binding Specificity: AA 454-482, C-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-482 amino acids from the C-terminal region of human TNIP1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TNIP1

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Alternative Name: TNIP1

Background: Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal (By similarity). Increases cell surface CD4(T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.

Molecular Weight: 71864

Gene ID: 10318

NCBI Accession: NP_001239315, NP_001239319, NP_001239320, NP_001239321, NP_001239322, NP_001245383, NP_006049

UniProt: Q15025

Pathways: Activation of Innate immune Response