FBLIM1 antibody (C-Term)

Catalog No. ABIN2845889

This Rabbit Polyclonal antibody specifically detects FBLIM1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FBLIM1 antibody (C-Term) (ABIN2845889)

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBLIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32318

Product Details anti-FBLIM1 Antibody

Binding Specificity: AA 294-323, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FBLIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-323 amino acids from the C-terminal region of human FBLIM1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FBLIM1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for FBLIM1

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Alternative Name: FBLIM1

Background: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 40670

Gene ID: 54751

NCBI Accession: NP_001019386, NP_001019387, NP_060026

UniProt: Q8WUP2