EGF antibody (Center)

Catalog No. ABIN656805

This anti-EGF antibody is a Rabbit Polyclonal antibody detecting EGF in WB and IHC (p). Suitable for Human and Mouse.

Quick Overview for EGF antibody (Center) (ABIN656805)

Target: EGF (Epidermal Growth Factor (EGF))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EGF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB16555

Product Details anti-EGF Antibody

Binding Specificity: AA 690-720, Center

Specificity: This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 689-720 amino acids from the Central region of human EGF.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-720 AA from the Central region of human EGF.

Isotype: Ig Fraction

Application Details

Application Notes: WB = 1:1000, IHC (p) = 1:10-50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: EGF Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for EGF

Target: EGF (Epidermal Growth Factor (EGF))

Alternative Name: EGF

Background: This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
Synonyms: Pro-epidermal growth factor,EGF,

Molecular Weight: 133994 DA

Gene ID: 1950

NCBI Accession: NP_001954

UniProt: P01133

Pathways: NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation