Beclin 1 antibody (AA 150-300)

Catalog No. ABIN363641

The Rabbit Polyclonal anti-Beclin 1 antibody is suitable to detect Beclin 1 in samples from Human, Mouse, Rat, Monkey, Pig and Xenopus laevis. It has been validated for WB, IHC, IF, ICC, IP and IHC (p).

Quick Overview for Beclin 1 antibody (AA 150-300) (ABIN363641)

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivity: Human, Mouse, Rat, Monkey, Pig, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Beclin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Beclin 1 Antibody

Binding Specificity: AA 150-300

Specificity: Reacts with human ~52 kDa Beclin 1 protein

Cross-Reactivity: Mouse (Murine), Cow (Bovine), Chicken, Pig (Porcine)

Cross-Reactivity (Details): Cross-react with protein. from mouse, rat, bovine, chicken, primate, porcine, Xenopus

Purification: Antigen affinity purified

Immunogen: Synthetic peptide made to an internal portion of the human protein (within residues 150-300)

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ICC/IF1:50, IHC1:400, IHC-P 1:400, WB1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, glycerol 50 % , BSA 0.1 %, Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for Beclin 1

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Alternative Name: Beclin-1

Background: Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

Gene ID: 8678

Pathways: Autophagy