BST1 antibody (APC)

Catalog No. ABIN2852498

The Mouse Monoclonal anti-BST1 antibody is suitable to detect BST1 in samples from Human and Non-Human Primate. It has been validated for FACS.

Quick Overview for BST1 antibody (APC) (ABIN2852498)

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This BST1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: SY11B5

Product Details anti-BST1 Antibody (APC)

Purpose: Anti-Hu CD157 APC

Cross-Reactivity (Details): Human, Non-Human Primates

Characteristics: The mouse monoclonal antibody SY11B5 recognizes CD157, an approximately 45 kDa GPI-anchored extracellular protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human CD157

Isotype: IgG1, kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze,Protect from prolonged exposure to light

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for BST1

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Alternative Name: CD157

Background: Bone marrow stromal cell antigen 1,CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates. CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role.,BST1, cADPr hydrolase 2

Gene ID: 683

UniProt: Q10588