KISS1R antibody (C-Term)

Catalog No. ABIN2854280

The Rabbit Polyclonal anti-KISS1R antibody has been validated for WB, ICC, IF and IHC (p). It is suitable to detect KISS1R in samples from Human. There is 1 publication available.

Quick Overview for KISS1R antibody (C-Term) (ABIN2854280)

Target: KISS1R (KISS1 Receptor (KISS1R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KISS1R antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KISS1R Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Rat

Characteristics: Rabbit polyclonal antibody to GPR54 (KISS1 receptor)
GPR54 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GPR54. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-KISS1R antibody (ABIN2854280)

Francis, Abera, Matjila, Millar, Katz: "Kisspeptin regulation of genes involved in cell invasion and angiogenesis in first trimester human trophoblast cells." in: PLoS ONE, Vol. 9, Issue 6, pp. e99680, (2015) (PubMed).

Target Details for KISS1R

Target: KISS1R (KISS1 Receptor (KISS1R))

Alternative Name: KISS1 receptor

Background: The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.

Cellular Localization: Cell membrane, Multi-pass membrane protein

Molecular Weight: 43 kDa

Gene ID: 84634

UniProt: Q969F8