Endothelin 2 antibody

Catalog No. ABIN2854413

This anti-Endothelin 2 antibody is a Rabbit Polyclonal antibody detecting Endothelin 2 in WB. Suitable for Human.

Quick Overview for Endothelin 2 antibody (ABIN2854413)

Target: Endothelin 2 (EDN2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endothelin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Endothelin 2 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to ET-2 (endothelin 2)
ET-2 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ET-2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Endothelin 2

Target: Endothelin 2 (EDN2)

Alternative Name: endothelin 2

Background: This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation.

Cellular Localization: Secreted

Molecular Weight: 20 kDa

Gene ID: 1907

UniProt: P20800

Pathways: Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones