Cytochrome P450 26B (Internal Region) antibody

Catalog No. ABIN2854494

The Rabbit Polyclonal anti-Cytochrome P450 26B antibody (ABIN2854494) specifically detects Cytochrome P450 26B in WB. The antibody is reactive with Human samples.

Quick Overview for Cytochrome P450 26B (Internal Region) antibody (ABIN2854494)

Target: Cytochrome P450 26B

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details

Binding Specificity: Internal Region

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Xenopus tropicalis

Cross-Reactivity (Details): Mouse (94 %), Rat (94 %), Bovine (94 %), Xenopus tropicalis (81 %)

Characteristics: Rabbit polyclonal antibody to Cytochrome P450 26B (cytochrome P450, family 26, subfamily B, polypeptide 1)
Cytochrome P450 26B antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Cytochrome P450 26B. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details

Target: Cytochrome P450 26B

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid.

Cellular Localization: Endoplasmic reticulum membrane, Peripheral membrane protein , Microsome membrane, Peripheral membrane protein , Endoplasmic reticulum membrane , Microsome membrane

Molecular Weight: 58 kDa

Gene ID: 56603