TAZ antibody (C-Term)

Catalog No. ABIN2854556

The Rabbit Polyclonal anti-TAZ antibody has been validated for IHC (p). It is suitable to detect TAZ in samples from Human.

Quick Overview for TAZ antibody (C-Term) (ABIN2854556)

Target: TAZ (Tafazzin (TAZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAZ antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TAZ Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to TAZ (tafazzin)
TAZ antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Tafazzin / TAZ. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TAZ

Target: TAZ (Tafazzin (TAZ))

Alternative Name: tafazzin

Background: This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced, the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Cellular Localization: Isoform 1: Membrane, Single-pass membrane protein , Isoform 2: Cytoplasm , Isoform 3: Membrane, Single-pass membrane protein , Isoform 4: Membrane, Single-pass membrane protein , Isoform 5: Membrane, Single-pass membrane protein , Isoform 6: Cytoplasm , I

Molecular Weight: 33 kDa

Gene ID: 6901

UniProt: Q16635